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2-methyl-5-nitroimidazole

khoom

2-methyl-5-nitroimidazole Featured duab
  • 2-methyl-5-nitroimidazole

2-methyl-5-nitroimidazole

Cov ntaub ntawv tseem ceeb:

Lub npe tshuaj: 2-methyl-5-nitroimidazole;
Lub npe Askiv: 2-Methyl-5-nitroimidazole;
CAS Nr .: 88054-22-2
Cov mis mos molecular: C4H5N3O2
Molecular Luj: 127.1
PIB: 618-108-7
Tus qauv qauv:

kev 2

Yam khoom muaj xws li: raw khoom; Pharmaceutical intermediates; Pharmaceutical raw khoom.


Product Detail

Khoom cim npe

Physicochemical khoom

Qhov ceev: 1.4 ± 0.1g / cm3

Kub taw tes: 399.5 ± 15.0 ° C ntawm 760 mmHg

Melting point: 252-254ºC

Lub teeb taw tes: 195.4 ± 20.4 ° C

PIB: 127.038177

PSA: 74.50000 LogP:-0.10

Cov tsos: Dawb crystal

Vapor siab: 0.0 ± 0.9 mmHg ntawm 25 ° C

Refractive Index: 1.592

Cia tej yam kev mob: kaw nyob rau hauv ib tug txias thiab qhuav qhov chaw ntawm 0-6 ºC

Stability: nws yuav tsis decompose thaum siv thiab khaws cia raws li kev cai.

Specification Index

specification chav tsev txheem
Qhov tshwm sim   Zoo li cov hmoov dawb los yog daj daj
Cov ntsiab lus % ≥99%
Moisture % ≤0.3
Sulfate % ≤0.3

 

Khoom siv

Feem ntau siv nyob rau hauv synthesis ntawm metronidazole, dimetazole thiab lwm yam tshuaj intermediates.

ntau lawm

Nws tau txais los ntawm nitration ntawm 2-methylimidazole. Muab sulfuric acid, 2-methylimidazole thiab sodium sulfate rau hauv cov tshuaj tiv thaiv lauj kaub, do thiab cua sov, ntxiv nitric acid ntawm 150-160 ℃, ntxiv, ua raws li cov tshuaj tiv thaiv hleb rau 1 teev. Tshem tawm qhov kub ntawm 140 ℃ hauv qab no, tom qab ntxiv dej nrog ammonia dej los kho cov pH rau 3.5-4, crystallization. Lim, ntxuav kom nruab nrab, qhuav, 2-methyl-5-nitroimidazole.

Specifications thiab cia

25k kraft ntawv hnab los yog lub hnab woven (58 × 110) lined nrog lub hnab yas, 250kg export thawv hnab (100 × 80); Raws li cov neeg siv khoom xav tau;
Kev kaw cia, khaws cia rau hauv qhov chaw txias, tsaus, qhuav warehouse, cia thiab tsheb thauj mus los yuav tsum yog lub teeb, tiv thaiv kev puas tsuaj thiab noo noo, txwv tsis pub cov tshuaj sib xyaw.

Txoj kev tsim khoom: Tau txais los ntawm nitration ntawm 2-methylimidazole. Muab sulfuric acid, 2-methylimidazole thiab sodium sulfate rau hauv cov tshuaj tiv thaiv lauj kaub, do thiab cua sov, ntxiv nitric acid ntawm 150-160 ℃, ntxiv, ua raws li cov tshuaj tiv thaiv hleb rau 1 teev. Tshem tawm qhov kub ntawm 140 ℃ hauv qab no, tom qab ntxiv dej nrog ammonia dej los kho cov pH rau 3.5-4, crystallization. Lim, ntxuav kom nruab nrab, qhuav, 2-methyl-5-nitroimidazole.

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