5-nitroisophthalic acid
Cov ntaub ntawv tseem ceeb:
Taw qhia: 5-nitroisophthalic acid yog ib qho tseem ceeb ntawm cov khoom nruab nrab rau cov tsis-ionic contrast agents xws li iodohexyl cawv, iodoparol, iodoformol, thiab lwm yam. Nws kuj yog cov khoom pib rau disperse dyes 2, 6-dicyano-4-nitroaniline, uas muaj ntau yam kev siv thiab kev lag luam zeem muag.
Lub npe tshuaj: 5-nitroisophthalic acid; 5-nitro-1, 3-phthalic acid
CAS Nr .: 618-88-2
Cov mis mos molecular: C8H5NO6
Molecular Luj: 211.13
EINECS tus xov tooj: 210-568-3
Cov qauv qauv:
Yam khoom muaj feem: Organic chemical raw khoom; Pharmaceutical intermediates;
Melting point: 259-261 ° C (lit.)
Kub taw tes: 350.79 ° C (nrog kwv yees)
Qhov ceev: 1.6342 (nruab nrab kwv yees)
Refractive Index: 1.5282 (kwv yees)
Kev kub ceev: 120 ° C
Solubility: Soluble hauv cawv, ether thiab dej kub
khoom: dawb rau dawb hmoov.
Vapor siab: 0.0 ± 1.2 mmHg ntawm 25 ° C
| specification | chav tsev | txheem |
| Qhov tshwm sim | Dawb rau dawb hmoov | |
| Cov ntsiab lus | % | ≥99% |
| Moisture | % | ≤0.5 |
Ib qho tseem ceeb nruab nrab rau disperse dyes. Nws kuj yog qhov nruab nrab ntawm cov tshuaj ntsuam xyuas cov tshuaj tshiab ubiquitin (X-ray contrast agent); Nws kuj yog siv los ua ke cov tshuaj tshiab tshuaj raws li PDE IV inhibitor glycolinic acid; Nws kuj yog siv los ua ib qho nruab nrab rau disperse dyes (xiav azo dyes).
Concentrated sulfuric acid (104.3mL, 1.92mol) tau ntxiv rau hauv peb lub raj mis, tom qab ntawd isophthalic acid (40g, 0.24mol) ntxiv, nplawm thiab rhaub rau 60 ℃, tuav rau 0.5h, thiab 60% nitric acid (37.8g, 0.36). mol) tau ntxiv los tswj qhov kev ua kom nrawm nrawm. Ntxiv nws hauv 2 teev. Tom qab ntxiv, cov tshuaj tiv thaiv tshav kub ntawm 60 ℃ rau 2 teev. Txias kom qis dua 50 ° C, tom qab ntawd ntxiv 100mL dej. Cov khoom siv tau txias rau hauv chav tsev kub, nchuav rau hauv lub lim, tso tawm kom tshem tawm cov kua qaub pov tseg, lim ncuav mog qab zib yog ntxuav nrog dej, drained rau recrystallize, thiab cov khoom dawb yog 34.6 grams, yield yog 68.4%.
25kg / 3-hauv-1 hnab ntawv-yas composite hnab, los yog woven hnab, los yog 25kg / cardboard thoob (φ410 × 480mm); Ntim raws li cov neeg siv khoom xav tau;
Khaws rau hauv ib lub thawv airtight nyob rau hauv ib qho chaw txias, qhuav, zoo-ventilated qhov chaw deb ntawm hluav taws thiab combustibles.
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